Citation data is made available by participants in crossrefs citedby linking service. Beauv and clerodendron splendens a cheval are known. This page was last edited on 19 august 2018, at 12. Comparison of commercially available multiplex rat cytokine methods. Uvaria chamae was extracted with ethanol, and administered orally to rats at doses ranging from 200 to 5000 mgkgday for 28 days while distilled water was administered to the control group, the survived animals 43 %, were then euthanized, and blood collected for biochemical and haematological markers. It is taken internally in the treatment of catarrhal inflammation of the mucous membranes. Pdf evaluation of invivo antisalmonella activity of.
In ethiopia, people use different plant species to treat malaria. Full text effects of caralluma russeliana stem extract. Title african flowering plants database publication author website. Their constituents were extracted and then fractionated in order to isolate the active ingredients. The purpose of this study was to evaluate the antioxidant activity of compounds isolated from clerodendrum splendens leaves. Isolation and characterization of compounds from the stem bark of uvaria rufa annonaceae 53 experiments of hmbc as shown in a and hh cosy in b established the final structure of benzyl benzoate. Effects of caralluma russeliana stem extract on some physiological parameters in streptozotocininduced diabetic male rats talal a zari, mesfer a althebaiti department of biological sciences, faculty of science, king abdulaziz university, jeddah, saudi arabia purpose. Pdf phytochemical composition and biological activities of uvaria. Phytochemical compositions in some nigerian medicinal. Antibiofilm activity of prosopis africana and uvaria chamae extracts against. Create your own buttonbadge designs online with the buttonmaker2, powered by smart grafx. Files are available under licenses specified on their description page.
The majority of the ethiopian population is at risk of malaria largely caused by plasmodium falciparum. Pdf the roots of plumbago zeylanica plumbaginaceae and uvaria chamae annonaceae have been used in folklore medicine in the management of. Beauv annonaceae offers alternative treatment for diabetes mellitus. Evaluation of the antiplasmodial properties of selected. Several researches have been carried out in order to explore and identify the chemical compositions responsible for various pharmacological.
Phytochemical composition, antioxidant and antibacterial. The finding of the study will help inform decision regarding improved policy responses in screening of highrisk population and public health management of the disease across the rural communities within the region and in nigeria as a whole. One should not drive a vehicle if using the medicine makes you drowsy, dizzy or lowers your bloodpressure extensively. Genetic transformation was confirmed by epifluorescence and plagiotropic hairy root growth in absence of growth regulators. Uvaria is a genus of flowering plants in the soursop family, annonaceae. The leaves and roots of uvaria chamae are rich in natural. Pharmacists also advise patients not to drink alcohol with.
Access is allocated within two business days of purchase and lasts one year. For a more comprehensive list of citations to this article, users are encouraged to. Evaluation of invivo antisalmonella activity of uvaria. Uvaria chamae is a medicinal plant that is used in many parts of the world in the treatment of diabetes, and other diseases. Fresh uvaria chamae leaves and roots were air dried, pulverized and extracted. Nigeria is naturally blessed with both savannah and tropical rainforests vegetation and these offer a wide distribution of plants believed to possesses secondary metabolites which are responsible for treating or curing various diseases. Bmc complementary medicine and therapies home page.
However, very few of them have so far been evaluated. It has been reported that extracts of uvaria chamae have mutagenic effects. It is the goal of my research in particular, to elucidate both the effects and the mechanisms of action of the herbal medicine or complementary and alternative medicine cam using animal models of stressrelated diseases such as anxiety, depression, insomnia or learning and memory. Molecular mechanisms of inhibition of streptococcus. An ethnobotanical survey was carried out between march 2016 and august 2016 to obtain relevant information about medicinal plants used in the treatment of malaria in nsukka local government area of enugu state, southeastern nigeria. Evaluation of invivo anti salmonella activity of uvaria. The leaves of clerodendrum splendens are used in traditional medicine by indegenous people to treat shingles, spleen in children, asthma, rheumatism, ulcers and malaria. Research article antibacterial activity of chalcone and. Issued as a pdf on the internet, it contains basic information on over 250 species of plants used for food in benin. Annonaceae is a speciesrich genus of woody climbers and scandent shrubs, widespread in wet tropical forests in africa, madagascar, continental asia, malesia, northern australia and melanesia.
Diabetes mellitus has been a menace to mankind from time immemorial. Uvaria chamae, commonly known as finger root or bush banana is a climbing large shrub or. Haematological effect of ethanolic extract of uvaria chamae on monosodium glutamate msg induced toxicity in spraguedawley rats ibukun o. Evaluation of antitrypanosomal and anti inflammatory. Uvaria chamae is a plant with both medicinal and nutritional values. Chemical constituents of clerodendrum splendens lamiaceae. This study aims to analyze the chemical compounds and evaluate the antiradical and antisalmonellaactivities of extracts from sarcocephalus latifolius, lannea barteri, uvaria chamae, parkia biglobosaand khaya senegalensis using respectively standards phytochemical methods, phosphomolybdates reduction method and micro dilution method in liquid medium associated. Medicinal plants used by the people of nsukka local. This study aimed to produce scientific data on in vitro and in vivo efficacy of uvaria chamae, lantana camara and phyllantus amarus on. Odesanmi 4 1national agency for food and drug, administration and control, ilorin, nigeria. In vivo and in vitro studies carried out by many researchers have shown that.
If you experience drowsiness, dizziness, hypotension or a headache as sideeffects when using uvaria chamae medicine then it may not be safe to drive a vehicle or operate heavy machinery. The potentials of uvaria chamae as an antidiabetic and hypolipidemic drugcandidate are thus tested. This work will be of significant interest to scientists, researchers, medical practitioners, pharmacologists, ethnobotanists, horticulturists, food nutritionists, agriculturists, botanists, herbalogists. Uvaria chamae annonaceae, is an essential oil bearing plant. Uvaria chamae is one of such plants used traditionally to treat diabetes mellitus and other conditions such as. Antibacterial activity of chalcone and dihydrochalcone. The roots of the plants were collected in the esan central region of edo state, nigeria. A new cytotoxic acetogenin, chamuvarinin 1, containing a tetrahydropyran ring with an adjacent bistetrahydrofuran ring, which corresponds to a novel carbon skeleton in this series, was isolated from the roots of uvaria chamae, together with the previously reported acetogenins squamocin 2, desacetyluvaricin 3, and neoannonin 4.
Issued as a pdf on the internet, it contains basic information on over 250 species of plants used for food. Phytoconstituants of two extracts of uvaria chamae tannins, flavonoids, and phenols were also. This multicompendium is a comprehensive, illustrated and scientifically uptodate work covering more than a thousand species of edible medicinal and nonmedicinal plants. Pdf in vitro antisickling activities and phytochemical evaluation of. Enjoy unrestricted access to all content and features, including.
In this study, we evaluated the acute and subchronic oral toxicity and safety of the aqueous root extract of uvaria chamae in. The resistance of the parasite to existing drugs is the main challenge in the control of the disease and thus new therapeutic drugs are required. The mutagenic effects of chamuvaritin, a dihydrobenzylchalcone isolated from uvaria chamae, were investigated using salmonella typhimurium tester strains ta92, ta9498, ta1001535, ta1537 and ta1538. Antidiabetic and hypolipidemic activities of hydroethanolic root. The drug benzyl benzoate used in antifungal preparations has a mutagenic compound, chamuvaritin, a benzyl dihydrochalcone that was isolated from uvaria chamae 10. Pdf phytochemical composition, antioxidant and antibacterial. All structured data from the file and property namespaces is available under the creative commons cc0 license. Odewo, a taxonomist in the department of botany and microbiology, faculty of science, university of lagos, nigeria. This study presents antimicrobial properties of uvaria chamae roots, commonly used for the. Pdf diabetes mellitus has been a menace to mankind from time immemorial.
The ones marked may be different from the article in the profile. Beauv and clerodendron splendens a cheval are known to have various medicinal and therapeutic properties. Pdf in the present work phytochemical composition, antioxidant and antibacterial. Antidiabetic effects of the ethanolic root extract of. A quantitative documentation of the composition of two powdered herbal formulations antimalarial and haematinic using ethnomedicinal information from ogbomoso, nigeria adepoju tunde joseph ogunkunle, tosin mathew oyelakin, abosede oluwaseyi enitan, and funmilayo elizabeth oyewole environmental biology unit, department of pure and applied. To learn about our use of cookies and how you can manage your cookie settings, please see our cookie policy. Uvaria chamae annonaceae, phyllantus amarus phyllantaceae and lantana camara verbenaceae are empirically alleged to be used as beninese medicinal plants in the treatment of salmonellosis. Pdf various parts of uvaria chamae are used by traditional medicine. Uvaria chamae is a climbing shrub or small tree growing up to 4 metres tall328. Uvaria chamae is a plant commonly used to cure diseases and heal injuries. Phytochemical composition and biological activities of uvaria. Phytochemical composition, antioxidant and antibacterial activities of root of uvaria chamae p. In vitro antiradical and antisalmonella activities of.
Unona macrocarpa vahl unona macrocarpa vahl ex dunal uva chamae kuntze uva cristata kuntze uva cylindrica kuntze uvaria cristata r. Antimicrobial susceptibility tests were performed against several multidrugresistant bacteria using the mueller hilton well agar. By closing this message, you are consenting to our use of cookies. Chamuvarinin, an acetogenin bearing a tetrahydropyran ring. The study aimed at evaluating antidiabetic activity of the ethanolic root extract of u. Antidiabetic effects of the ethanolic root extract of uvaria chamae p. However, research is needed to ascertain the beneficial and adverse effects of the consumption of the extract.
This study presents antimicrobial properties of uvaria chamae roots, commonly used for the treatment of various infections in south benin. New dihydrochalcones and flavanones from uvaria angolensis. The potentials of uvaria chamae as an antidiabetic and hypolipidemic drug candidate are thus tested. Histopathological examination of the pancreas, liver. Graviola inhibits hypoxiainduced nadph oxidase activity in prostate cancer cells reducing their proliferation and clonogenicity. The common name refers to the fruit growing in its small bunches. Create your own button designs online with the buttonmaker2, powered by smart grafx. Effects of uvaria chamae root extracts on cortisol, insulin, and testosterone in normal and streptozotocininduced diabetic rats f. Pdf antidiabetic effects of the ethanolic root extract. This study aimed to produce scientific data on in vitro and in vivo efficacy of uvaria chamae, lantana camara and phyllantus amarus on multiresistant salmonella spp isolated in. Improving the production of podophyllotoxin in hairy roots. Cytotoxicity was determined using the sulforhodamine b method, and the. A quantitative documentation of the composition of two.
This cited by count includes citations to the following articles in scholar. Haematological effect of ethanolic extract of uvaria. Please note that this is a trial program and may end. The phytochemical was mutagenic in tester strains ta98 and ta100 and required activation by the hepatic s9 microsomal enzyme preparation. Really good app for what it does, has almost everything we need compared to the big pdf editors like adobe acrobat.
Department of medical biochemistry, college of medical sciences, university of benin, benin, nigeria a327. The extracts reduced the incidence of paw oedema from 0. Graviola inhibits hypoxiainduced nadph oxidase activity. The generic name uvaria is derived from the latin uva meaning grape, likely because the edible fruit of some species in the genus resemble grapes. Download fulltext pdf download fulltext pdf download fulltext pdf download fulltext pdf evaluation of invivo antisalmonella activity of uvaria. Header bar uvimage editor header the header bar contains several menus and options for working with uvs view menu tools for, working with the editor and controlling how things are displayed. Multistage carcinogenesis in the urinary bladder, british medical bulletin, volume 36, issue 1, 1 january 1980, pages 3946, s. The aim of this study was to investigate the effects of caralluma russeliana stem extract on some physiological. The genus is characterized by a combination of features, including stellate hairs, generally valvate sepals, partially or fully. The drug benzyl benzoate used in antifungal preparations has a mutagenic compound. Uvaria chamae, commonly known as finger root or bush banana is a climbing large shrub or small tree native to tropical west and central africa where it grows in wet and dry forests and coastal scrublands.
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